沙眼是一种免疫病理性疾病,伴有血管翳和瘢痕的更为严重的进行性沙眼,只发生于再次感染后,这是根据对32户家庭持续10年的临床与实验室观察结果得出的结论。虽然大多数活动性沙眼能自然愈合,但有9户中26人发生29起新的沙眼感染,在不同的感染期导致慢性沙眼的证据。关于沙眼是再感染性疾病设想的进展通常认为沙眼的发病机理是青年期眼受衣原体感染,经过疾病发展的各个阶段,最后导致成年期角膜和结膜的瘢痕及转入静止期,但这一概念不符合作者观察结果。人体研究作者在台湾儿童中,对沙眼的自然发展史作了一些全面的观察,其中部分与沙眼疫苗及与抗生素治疗有一定的关 Trachoma is an immunopathological condition with more severe progressive trachoma associated with angiostenosis and scarring, occurring only after reinfection, based on clinical and laboratory observations of 32 families for 10 years Conclusion. Although most of the active trachoma naturally healed, 29 new trachoma infections occurred in 26 of 9 people and evidence of chronic trachoma at different stages of infection. Progress on the idea of ​​trachoma as a re-infective disease It is generally accepted that the pathogenesis of trachoma is infection of the chlamydial eye with chlamydia at each stage of the disease and eventually leads to scarring and transitional periods of adulthood and conjunctiva, but this concept Does not meet the author’s observations. The author of the study of human body made some comprehensive observations of the natural history of trachoma among Taiwanese children, some of which were related to trachoma vaccine and treatment with antibiotics