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目的调查抗菌药物临床应用现状,探讨抗菌药物的合理应用方法,避免临床上滥用抗菌药物。方法选择2009～2010年我市某市级医院使用抗菌药物的处方,对照《抗菌药物临床应用指导原则》进行合理性分析。结果共抽取抗菌药物处方9260张,其中不合理应用抗菌药物处方821张,占8.86%,抗菌药物的不合理应用主要有用法不正确、滥用抗生素、选药不合理、联合用药不合理、用量过大,其中以用法不正确为主。结论为了使抗菌药物的应用合理化,医疗机构应该根据《抗菌药物临床应用指导原则》,结合本医疗机构实际情况定期举办抗菌药物知识的讲座,加强用药指导,制定抗菌药物临床应用实施细则,建立健全的监督管理制度,是保证抗菌药物合理应用的重要基础。
Objective To investigate the status of clinical application of antibacterials and explore the rational application of antibacterials to avoid the abuse of antibacterials clinically. Methods The prescriptions of antibacterials used in a municipal hospital in our city from 2009 to 2010 were selected and the reasonableness of the guidelines of clinical application of antibacterials was analyzed. Results A total of 9,260 antibacterial prescriptions were drawn, among which 821 antibacterial prescriptions were unreasonably applied, accounting for 8.86%. The irrational use of antibacterials was mainly due to incorrect usage, abuse of antibiotics, irrational drug selection, unreasonable combination and unreasonable dosage Large, of which the usage is not correct. Conclusion In order to rationalize the application of antimicrobial agents, medical institutions should regularly hold lectures on antimicrobial knowledge in accordance with the Guiding Principles for the Clinical Application of Antibacterials, strengthen the guidance on the use of antimicrobial agents, formulate the implementation details of the clinical application of antimicrobial agents, and establish and perfect The supervision and management system is an important basis for ensuring the rational use of antimicrobial agents.