神经纤维瘤病在临床中较少见,合并马德隆畸形就更少见,我院在临床工作中遇到1例,现报告如下。1病历摘要女,5岁。家属无意中发现患儿左腕部肿胀畸形(无外伤史),体检,智力正常,全身皮肤遍布大小不等结节,左上臂外侧可见色素沉着,毛发密集,左腕畸形,X线显示,桡骨远端、掌骨、指骨 Neurofibromatosis is rare in clinical practice, combined with Madeleine deformity is even more rare, our hospital encountered 1 case in clinical work, are as follows. 1 medical records female, 5 years old. Family members inadvertently found that the left wrist of children with swelling and deformity (no history of trauma), physical examination, mental normal nodules throughout the body size ranging from the outside, left upper arm visible hyperpigmentation, hair-intensive, left wrist deformity, X-ray display, distal radius , Metacarpal, phalanx