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目的临床抗菌药物不合理用药情况分析及对策,为临床抗菌药物的合理应用提供依据。方法回顾性分析我院4000张门诊以及住院处方所用抗菌药物处方,并统计分析抗菌药物使用处方数及不良反应处方情况。结果选取的4000张处方中,经过统计发现有1360张处方为抗菌药物处方,其占总处方数的34.0%,通过对1360张抗菌药物处方进行分析发现,其中有385张处方中存在不合理用药现象,占28.3%。通过进行统计分析发现,抗菌药物不合理应用情况主要有以下几点:选择不合理、重复给药以及给药方式不合理、溶媒选用不当、理化禁忌、无指征滥用药物、药理拮抗等。结论临床应严格按照抗菌药物使用原则进行用药,不断加强定期控制抗菌药物应用的监督管理,以提高药物应用的合理性。
Objective Analysis and countermeasures of irrational use of clinical antibacterial drugs, provide basis for the rational application of clinical antibacterials. Methods A retrospective analysis of 4,000 outpatient clinics and inpatients used antibacterial prescriptions, and statistical analysis of the number of prescriptions for antibacterials and prescription of adverse reactions. Results Among the 4,000 prescriptions selected, 1,360 prescriptions were found to be antibacterial prescriptions, accounting for 34.0% of the total prescriptions. An analysis of 1,360 prescriptions for antibacterials found that 385 prescriptions contained unreasonable medication Phenomenon, accounting for 28.3%. Through statistical analysis found that the irrational use of antimicrobial drugs mainly in the following points: the choice of unreasonable, repeated administration and administration of unreasonable, improper solvent selection, physical and chemical taboo, no indication of drug abuse, pharmacological antagonism. Conclusion Clinical should be strictly in accordance with the principles of the use of antimicrobial agents medication, and constantly strengthen the regular control of the supervision and management of antimicrobial applications to improve the rational use of drugs.