酒精是一种常见的肝脏毒物,过度饮酒会导致肝脏发生脂肪变性、坏死和再生,引起酒精性肝病(alcoholic liver disease,ALD)。ALD早期表现为可逆性的酒精性脂肪肝(alcoholic fatty liver,AFL),并可逐渐进展为酒精性肝炎、肝纤维化、肝硬化、甚至肝癌。在欧美发达国家,酒精一直是引起肝脏疾病的重要因 Alcohol is a common liver poison. Excessive alcohol consumption can lead to fatty degeneration, necrosis and regeneration of the liver, resulting in alcoholic liver disease (ALD). ALD early manifestations of reversible alcoholic fatty liver (alcoholic fatty liver, AFL), and can progress to alcoholic hepatitis, liver fibrosis, cirrhosis, and even liver cancer. In developed countries in Europe and the United States, alcohol has been an important cause of liver disease