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目的:观察分析子宫肌瘤剔除术中联合应用垂体后叶素以及缩宫素的临床效果。方法:将我院82例腹腔镜子宫肌瘤剔除术患者根据双盲法分为研究组(联合应用垂体后叶素以及缩宫素治疗)和对照组(单独采用缩宫素治疗),对比分析两组患者用药后血压水平变化情况、手术相关情况以及术后情况等。结果:研究组患者用药后15 min、用药后30 min收缩压以及舒张压相对于对照组均明显升高(P<0.05),两组患者用药后1 h收缩压以及舒张压并没有很大差异(P>0.05)。两组患者剔除肌瘤直径以及剔除肌瘤个数并没有很大差异(P>0.05),但是研究组患者手术时间以及术中出血量等情况均明显少于对照组(P<0.05);研究组患者术后排气时间并没有很大区别(P>0.05),研究组患者住院时间明显短于对照组(P<0.05)。结论:腹腔镜子宫肌瘤剔除术中联合应用垂体后叶素以及缩宫素,可有效减少患者术中出血量,安全性较高,可在临床上广泛推广应用。
Objective: To observe the clinical effect of combined application of pituitrin and oxytocin in myomectomy. Methods: 82 cases of myeloma in laparoscopic myomectomy patients were divided into study group (combination of pituitrin and oxytocin treatment) and control group (treated with oxytocin alone) according to double-blind method, and comparative analysis Two groups of patients after treatment blood pressure levels, surgical conditions and postoperative condition. Results: The systolic blood pressure and diastolic blood pressure in study group were significantly increased at 15 min and 30 min after administration (P <0.05), and the systolic and diastolic blood pressure did not differ significantly at 1 h after treatment (P> 0.05). There was no significant difference between the two groups in terms of the diameter of myoma and the number of fibroids removed (P> 0.05). However, the operation time and intraoperative blood loss in the study group were significantly less than those in the control group (P <0.05) There was no significant difference in postoperative exhaust time between the two groups (P> 0.05). The hospitalization time of the study group was significantly shorter than that of the control group (P <0.05). Conclusions: Laparoscopic myomectomy combined with pituitrin and oxytocin can effectively reduce the amount of intraoperative blood loss and has high safety. It can be widely applied in clinic.