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美国 FDA 批准使用活化的环磷酰胺。该药用于治疗白血病、淋巴瘤和其它癌症,而其活化形式,则可作为一种骨髓净化药,用于治疗急性骨髓性白血病的患者。这些患者经常规药物治疗后病情多次得到缓解,并要求进行自身骨髓移植。这种疗法的具体过程为:在进行高剂量的化疗和放疗之前,先抽取一部分患者骨髓,然后净化其中的白血病细胞,再将净化过的骨髓输回患者骨髓。
The US FDA approved the use of activated cyclophosphamide. This medicine is used to treat leukemia, lymphoma, and other cancers, and its activated form can be used as a bone marrow purifier for the treatment of patients with acute myeloid leukemia. These patients were relieved several times after routine medical treatment and required their own bone marrow transplantation. The specific process of this therapy is: Before high-dose chemotherapy and radiotherapy, first extract a part of the patient’s bone marrow, then purify the leukemia cells, and then return the purified bone marrow to the patient’s bone marrow.