血小板的粘附、聚集与释放等功能对血栓形成与止血具有重要意义,故血小板聚集试验(包括体外及体内聚集)已广泛地被采用于临床诊疗及科研工作。本文对影响血小板聚集的物质,包括聚集诱导剂、聚集抑制剂、释放诱导剂、释放抑制剂等及其作用机理,加以综述。同一物质常可具有数种作用,如既能诱导聚集,也能诱导释放。有时同一物质由于浓度的不同而出现不同作用。有些相同作用的物质,互相间具有协同作用。不同的物质使血小 Platelet adhesion, aggregation and release of other functions on thrombosis and hemostasis is important, so platelet aggregation test (including in vitro and in vivo aggregation) has been widely used in clinical diagnosis and research work. In this paper, the impact of platelet aggregation substances, including aggregation inducers, aggregation inhibitors, release inducing agents, release inhibitors and their mechanism of action, are reviewed. The same substance can often have several effects, such as inducing aggregation, but also induce the release. Sometimes the same substance can have different effects due to different concentrations. Some of the same role of material, synergy with each other. Different substances make the blood small