论文部分内容阅读
目的：运用心率变异（HRV）频谱分析法研究正常人和急性心肌梗死（AMI）患者心脏植物神经功能变化。方法：114例正常人和27例AMI患者先记录24h动态心电图，将全部窦性心率经计算机HRV软件处理后使心电信号转换为心率功率频谱（HRPS）。结果：正常人HRPS的低频段功率密度（PSD）、高频段功率密度在白天和夜间有明显的差异性（P＜0．01），白天低频段PSD明显增加，夜间高频段PSD明显增加；随着年龄的增加，低频段PSD和高频段PSD逐渐下降。AMI患者低频段PSD和高频段PSD与正常人比较明显降低（P＜0．01），且无白昼生理波动，这说明AMI患者支配心脏的交感神经和迷走神经均受损。结论：HRV频谱分析对评价心脏植物神经功能是一种敏感而无创的检测指标。
Objective: To study the functional changes of cardiac autonomic nerve in normal subjects and patients with acute myocardial infarction (AMI) by heart rate variability (HRV) spectral analysis. Methods: 114 healthy subjects and 27 AMI patients were recorded 24h dynamic electrocardiogram, all sinus heart rate by computer HRV software to transform the ECG signal into heart rate power spectrum (HRPS). Results: The HR PSD of low frequency band and high frequency band of HRPS were significantly different between daytime and nighttime (P <0.01), the PSD of low frequency band increased significantly during nighttime and the nighttime high frequency band increased significantly. With the increase of age, the low frequency band PSD and the high frequency band PSD gradually decline. The low-frequency PSD and high-frequency PSD of AMI patients were significantly lower than those of normal subjects (P <0.01), and there was no physiological fluctuations in daylight. This indicated that the sympathetic and vagal nerves dominated the heart of AMI patients were impaired. Conclusion: HRV spectral analysis is a sensitive and noninvasive detection index for evaluating cardiac autonomic nerve function.