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目的评价依科源牌舒压胶囊对自发性高血压大鼠(SHR)降血压的作用。方法将SHR随机分为对照组及舒压胶囊0.15,0.30、0.90 g/kg剂量组,每组10只,另取SD大鼠20只,随机分为对照组和舒压胶囊高剂量组,每组10只,给予胶囊内容物30 d,实验前后及每周测量血压和心率。结果与对照组比较,舒压胶囊高剂量组能显著降低SHR的血压(P<0.01)。结论依科源牌舒压胶囊对SHR有良好的辅助降血压作用。
Objective To evaluate the effect of Yikeyuan Shuzao Capsule on lowering blood pressure in spontaneously hypertensive rats (SHR). Methods SHR were randomly divided into control group and Shuxin capsule 0.15, 0.30, 0.90 g / kg dose group, 10 rats in each group, and another 20 SD rats were randomly divided into control group and Shu pressure capsule high dose group Group 10, given capsule content 30 d, before and after the test and weekly measurement of blood pressure and heart rate. Results Compared with the control group, Shuxin Capsule high-dose group can significantly reduce the blood pressure of SHR (P <0.01). Conclusion Yikeyuan Shujin capsule has a good auxiliary hypotensive effect on SHR.