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炎性肌病为最大一组获得性肌病,表现为骨骼肌炎性浸润,伴肌纤维破坏.可分为已知病因的病毒性、细菌性等,及原因不明而有免疫机制异常者包括多发性肌炎(PM)、皮肌炎(DM)和包涵体肌炎(IBM)等.与自身免疫病因有关的证据有:(1)伴发其它自身免疫性疫病;(2)血清学试验有免疫状态改变;(3)除IBM外PM及DM均对免疫治疗有效.PM:常为散在单个肌纤维坏死,早期表现为透明变,随后单核吞噬细胞侵袭.肌肉中可见到单个或小簇状灶性分布的再生纤维.炎性细胞浸润
Inflammatory myopathy is the largest group of acquired myopathy, manifested as inflammatory infiltration of skeletal muscle, with destruction of muscle fibers can be divided into the known causes of viral, bacterial, etc., and unexplained and have abnormal immune mechanisms, including multiple (PM), dermatomyositis (DM) and inclusion body myositis (IBM), etc. Evidences related to the etiology of autoimmune diseases include: (1) with other autoimmune diseases; (2) with serological tests Immune status changes; (3) PM and DM outside DM are effective for immunotherapy.PM: often scattered in a single muscle fiber necrosis, the early manifestations of transparent change, followed by mononuclear phagocyte invasion. Muscle can be seen in single or small clusters Focal distribution of regenerative fibers. Inflammatory cell infiltration