目的观察消癥化瘀方联合高强度聚焦超声治疗子宫肌瘤的临床疗效。方法将120例子宫肌瘤患者随机分为研究组和对照组各60例。研究组患者给予消癥化瘀方联合高强度聚焦超声治疗,对照组患者行高强度聚焦超声消融治疗。分别与治疗前及治疗后3个月行超声检查,评价2组患者子宫大小、肌瘤平均体积、最大子宫肌瘤体积,计算2组患者平均瘤体缩小率。依据子宫肌瘤患者症状严重程度评分表对治疗前后患者的临床症状进行评分。结果治疗后,研究组子宫大小、肌瘤平均体积与最大子宫肌瘤体积减少程度均大于对照组,平均瘤体缩小率大于对照组,差异均有统计学意义(P<0.05)。治疗后2组症状严重程度评分较治疗前均有所降低,且研究组降低幅度大于对照组,差异均有统计学意义(P<0.05)。结论消癥化瘀方联合高强度聚焦超声刀治疗子宫肌瘤可以明显缩小子宫肌瘤体积,有效改善子宫肌瘤临床症状,提高患者生活质量。 Objective To observe the clinical efficacy of Xiaozhong Huayu Fang combined with high intensity focused ultrasound in the treatment of uterine fibroids. Methods 120 cases of uterine fibroids were randomly divided into study group and control group of 60 cases. Patients in the study group were treated with Xiaozhong Huayu Decoction combined with high-intensity focused ultrasound, while those in the control group were treated with high-intensity focused ultrasound ablation. Before treatment and 3 months after treatment, ultrasound examination was performed to evaluate the uterine size, fibroid average volume and maximal uterine myoma volume in the two groups. The average reduction rate of the two groups was calculated. The clinical symptoms of patients before and after treatment were scored according to the symptom severity scale of patients with uterine fibroids. Results After treatment, the size of the uterus, the average volume of myoma and the volume of the largest uterine fibroids in the study group were significantly larger than those in the control group. The average reduction rate of the tumors was larger than that of the control group (P <0.05). After treatment, the scores of symptom severity in both groups were lower than those before treatment, and the reduction in the study group was greater than that in the control group (P <0.05). Conclusion The combination of Xiaozheng Huayu decoction and high-intensity focused ultrasound knife in the treatment of uterine fibroids can significantly reduce the volume of uterine fibroids, effectively improve the clinical symptoms of uterine fibroids and improve the quality of life of patients.