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目的:探讨抑郁在围绝经期月经失调发病中的作用及中药联合高压氧干预效果。方法:①采用整群抽样与问卷调查方式对围绝经期妇女中月经失调患者964例,用SPSS 17.0建立数据库并进行统计学分析。②选择抑郁合并月经失调患者50例,对照分析中药联合高压氧干预后的效果。结果:①在调查的1798例围绝经期妇女中,月经失调患者964例,占53.6%,在964例月经失调患者中,抑郁者占54.3%(523/964),与月经失调的关系经检验(P<0.01),有相关性;且抑郁评分均值(49.97±10.15)明显高于国内常模。②中药联合高压氧干预对月经改善率为96.67(P<0.01);HAMD、E2、FSH两组比较均有显著差异(P<0.05)。结论:经初步调查分析显示,抑郁是围绝经期月经失调的重要因素;中药联合高压氧能有效改善围绝经期月经失调妇女的抑郁症。
Objective: To investigate the role of depression in the pathogenesis of menstrual disorders during perimenopause and the effect of combined Chinese medicine and hyperbaric oxygen therapy. Methods: (1) 964 cases of menstrual disorders in perimenopausal women were collected by cluster sampling and questionnaire. The data were analyzed by SPSS 17.0. ② 50 patients with depression and menstrual disorders were selected to analyze the effect of traditional Chinese medicine combined with hyperbaric oxygen intervention. Results: ① Among the 1798 perimenopausal women surveyed, 964 were menstrual disorders, accounting for 53.6%. Among the 964 cases of menstrual disorders, 54.3% (523/964) were depressed, and the relationship with menstrual disorders was tested (P <0.01), and the mean value of depression score (49.97 ± 10.15) was significantly higher than that of domestic norm. (2) The improvement rate of menstruation was 96.67 (P <0.01). The HAMD, E2 and FSH were significantly different between the two groups (P <0.05). Conclusion: After preliminary investigation and analysis, depression is an important factor in menopausal menstrual disorders; Chinese medicine combined with hyperbaric oxygen can effectively improve menopausal women with menopausal depression.