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二卤二(苯甲酰丙酮)合钛(Ⅳ)是西德Keller等人于1982年发现的一种新型具有抗癌活性的金属配合物。对小白鼠的 S-180瘤,Walker-256瘤和对黑色雄性 NMRT-鼠的L-1210瘤的抑制作用比目前已用于临床的抗癌药物——顺铂高,并且毒性比顺铂低得多。Keller的发现引起人们对这类配合物的
Dihalodibenzoyl acetonate (IV) is a novel metal complex with anticancer activity discovered by Keller et al. In West Germany in 1982. The inhibitory effect on mouse S-180 tumor, Walker-256 tumor and L-1210 tumor against black male NMRT-mouse is higher than cisplatin which is currently used in the clinical anticancer drug and is less toxic than cisplatin Much more. The discovery of Keller has caused people to work on such complexes