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用淀粉凝胶电泳法对我国汉族９个人群的红细胞酸性磷酸酶（ＡｃＰ１）、酯酶Ｄ（ＥｓＤ）、及６－磷酸葡萄糖酸脱氢酶（６－ＰＧＤ）的遗传多态性进行了研究。研究结果表明：兰州、呼和浩特、哈尔滨、西安、郑州、成都、贵阳、漳州、梅州等９市汉族人群的ＡｃＰＢ１基因频率依次为０．７９２９、０．８１６７、０．７９３８、０．８１３１、０．８０８８、０．８００５、０．７８９６、０．７７９４和０．７６７５；ＥｓＤ１基因频率依次为０．６４７３、０．６１４８、０．６４４３、０．６４３９、０．６４７５、０．６３０５、０．６２８７、０．５９０７和０．５８２５；６－ＰＧＯＡ基因频率依次为０．８８８１、０．９１４３、０．９３３０、０．９３１８、０．８７５６、０．９２１２、０．９１８８、０．９４６１和０．９３７５。ＥｓＤ１基因频率在中国南、北方人群间有差异，北方人群的ＥｓＤ１频率高于南方人群，随着北纬纬度由高向低，汉族人群ＥｓＤ１频率也随着从北向南降低。在中国汉族人群中，ＥｓＤ基因及６－ＰＧＤ基因分化比较显著，而ＡｃＰ基因分化则不显著
The genetic polymorphisms of erythrocyte acid phosphatase (AcP1), esterase D (EsD), and 6-phosphogluconate dehydrogenase (6-PGD) in 9 Chinese Han population were studied by using starch gel electrophoresis . The results showed that the frequencies of AcPB1 gene in Lanzhou, Hohhot, Harbin, Xi’an, Zhengzhou, Chengdu, Guiyang, Zhangzhou and Meizhou were 0.7929,0.8167,0.7938,0.8131,0. 8088,0.8005,0.7896,0.7794 and 0.7675 respectively. The frequencies of EsD1 gene were 0.6473, 0.6148, 0.6443, 0.6439, 0.6475, 0.6305 and 0.6287 , 0.5907 and 0.5825, respectively. The frequency of 6-PGOA gene was 0.8881, 0.9143, 0.9330, 0.9318, 0.8756, 0.9212, 0.9188, 0.9461 and 0 respectively. 9375. EsD1 gene frequency in South China and North populations are different, the northern population EsD1 frequency is higher than the southern population, with the north latitude from high to low, Han population EsD1 frequency also decreases with decreasing from north to south. In Chinese Han population, EsD gene and 6-PGD gene differentiation is more significant, while AcP gene differentiation is not significant