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针灸用于临床治疗腹痛已有上千年历史,回顾性研究显示针灸对消化性溃疡有治疗作用,但未有对照研究证实。我们对健康人作随机对照实验,证实电针“足三里”可显著抑制基础胃酸分泌和假饲刺激胃酸分泌,但对五肽胃泌素刺激的胃酸分泌影响不大。电针对胃酸的抑制是通过迷走神经中继和内源性吗啡旁路机制,作用于拔针后1小时内消失。针刺对胃酸分泌的远期影响各家报告不一,但都是非对照研究。
Acupuncture for clinical treatment of abdominal pain has been thousands of years of history, a retrospective study showed that acupuncture has a therapeutic effect on peptic ulcer, but no controlled studies confirmed. Our randomized controlled trials of healthy people, confirmed that electroacupuncture “Zusanli” can significantly inhibit basal gastric acid secretion and pseudo-feeding stimulate gastric acid secretion, but pentagastrin-stimulated gastric acid secretion little effect. Electroacupuncture inhibition of gastric acid is through the vagus nerve relay and endogenous morphine bypass mechanism, the role disappears within 1 hour after needle extraction. The long-term effects of acupuncture on gastric acid secretion vary in various reports, but are non-controlled studies.