T淋巴细胞在免疫应答的调节中起重要作用。T辅助细胞识别由巨噬细胞加工的抗原,同时也识别小鼠I A区、人HLA D区所编码的决定簇。 T辅助细胞受刺激而增殖,并直接或通过可溶性介质的分泌诱导其它淋巴样细胞分化成效应细胞群。反之,T抑制细胞似乎直接识别抗原及小鼠I J区编码的决定簇,识别后即被激活以抑制免疫应答。T细胞调 T lymphocytes play an important role in the regulation of immune responses. T helper cells recognize antigens processed by macrophages and also recognize determinants encoded by the mouse HLA region A and human HLA D regions. T helper cells are stimulated to proliferate and induce the differentiation of other lymphoid cells into effector cell populations either directly or through the secretion of soluble mediators. Conversely, T-suppressor cells appear to recognize directly the epitopes encoded by the antigen and the mouse I J region and are activated upon recognition to suppress the immune response. T cell modulation