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目的探讨经支气管针吸活检(TBNA)在非小细胞肺癌(NSCLC)术前淋巴结分期中的临床应用价值和安全性。方法对术前胸部增强CT检查疑有纵隔/肺门淋巴结转移的26例NSCLC患者行TBNA检查,并与术后病理检查结果进行对比。结果 TBNA的敏感性、特异性、准确性、阳性预测值和阴性预测值,分别是76%(38/50)、100%(31/31)、85.2%(69/81)、100%(38/38)和72.1%(31/43)。病理分型总符合率为92.3%(24/26)。术前采用TBNA的c-N分期与p-N分期对比准确率可达92.3%(24/26)。全组无严重并发症发生。结论经TBNA进行NSCLC术前淋巴结分期,具有较高的临床实用价值和安全性。
Objective To investigate the clinical value and safety of bronchial needle aspiration biopsy (TBNA) in preoperative lymph node staging of non-small cell lung cancer (NSCLC). Methods Twenty-six patients with NSCLC suspected to have mediastinal / hilar lymph node metastases underwent enhanced chest computed tomography (CT) before surgery underwent TBNA examination and compared with postoperative pathological findings. Results The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of TBNA were 76% (38/50), 100% (31/31), 85.2% (69/81), 100% / 38) and 72.1% (31/43). The total coincidence rate of pathological type was 92.3% (24/26). The accuracy of preoperative TBNA c-N staging compared with p-N staging was 92.3% (24/26). The whole group without serious complications. Conclusion TBNA preoperative NSCLC lymph node staging, has a high clinical value and safety.