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幽门螺杆菌抗体滴度随细菌消灭而下降。本文选144例患幽门螺杆菌感染者用抗菌治疗两周,然后用血清试验、细菌培养、胃标本组织学检查随访6周、6个月、12个月。试图找出抗体滴度何种程度的下降最能说明杆菌已根除。病人和方法选144例(男81、女63)平均年龄51.7(24.9～80)岁、经组织学及细菌培养诊断为幽门螺杆菌感染的病人。其中78例患十二指肠溃疡,16例胃溃疡,2例两者兼有,其余48例患慢性胃炎。全部病例经三联抗菌治疗两周。治疗前和治疗后6(±2)周、6(±2)月、12(±3)月随访,内容包括活检样本进行组织学检查、细菌培养,并送血清样本行幽门螺杆菌抗体检查。两周的治疗由胶体碱式枸橼酸铋(col-loidal bismuth subcitrate 120mg,每日4次)、灭滴
Helicobacter pylori antibody titer decreased with the elimination of bacteria. This article selected 144 cases of Helicobacter pylori infection with antibacterial treatment for two weeks, and then with serum test, bacterial culture, histological examination of gastric specimens were followed up for 6 weeks, 6 months, 12 months. Attempting to find out to what extent the drop in antibody titer best explains that bacilli have been eradicated. Patients and Methods 144 patients (male 81, female 63) with an average age of 51.7 (24.9-80) years were diagnosed as H. pylori infection by histology and bacterial culture. 78 cases of duodenal ulcer, 16 cases of gastric ulcer, 2 cases both, the remaining 48 cases of chronic gastritis. All cases were triple antibacterial treatment for two weeks. Pre-treatment and post-treatment 6 (± 2) weeks, 6 (± 2) months, 12 (± 3) months follow-up, including biopsy samples for histological examination, bacterial culture, and sent serum samples for H. pylori antibody test. Two weeks of treatment with colloidal bismuth bismuth citrate (col-loidal bismuth subcitrate 120mg, 4 times daily), drop off