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目的观察丹参酮Ⅱa注射液在心源性猝死患者心肺复苏中的作用。方法将30例心源性猝死患者随机分成两组,在常规进行心肺复苏的基础上,治疗组给予丹参酮Ⅱa注射液,对照组为生理盐水。观察两组患者自主循环恢复时间;同时检测患者肌酸激酶同工酶(CK-MB)、肌钙蛋白I(CTNI)、血浆B型利钠肽(BNP)水平。结果丹参酮Ⅱa注射液治疗组患者恢复有效自主循环时间较对照组缩短(P<0.05);两组患者CK-MB、CTNI、BNP均上升,但治疗组的升高幅度低于对照组。结论丹参酮Ⅱa注射液增加了心肺复苏的成功率,减轻复苏后的心肌损伤和改善复苏后患者心功能。
Objective To observe the effect of tanshinone Ⅱ a injection on cardiopulmonary resuscitation in patients with sudden cardiac death. Methods Thirty patients with sudden cardiac death were randomly divided into two groups. On the basis of routine cardiopulmonary resuscitation, tanshinone Ⅱ a injection was given to the treatment group and normal saline in the control group. The recovery time of spontaneous circulation in both groups was observed. The levels of CK-MB, CTNI and BNP were also measured. Results Tanshinone Ⅱa injection treatment group recovery effective autonomic circulation time shorter than the control group (P <0.05); CK-MB, CTNI, BNP were increased in both groups, but the treatment group increased less than the control group. Conclusion Tanshinone Ⅱ a injection can increase the success rate of cardiopulmonary resuscitation, reduce myocardial damage after resuscitation and improve cardiac function after resuscitation.