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目的研究和分析难治性癫痫早期预测因素,为临床上治疗提供理论上的依据。方法选择2009年11月2011年11月门诊患者200例,将其按病情分为两组,即实验组(120例)与对照组(80例)。观察患者一般资料,发作类型,家族史,疾病史,脑部损伤,精神状态和治疗效果。研究癫痫容易发展成难治性癫痫预测因素。结果实验组患者早期就有智能障碍(P<0.01)、治疗结束后脑电图检测显示仍然存在癫痫波样异常(P<0.01)、初次来院治疗前病情发作在10次以上(P<0.01)。结论治疗前癫痫发作次数多、伴有智能障碍、治疗结束后脑电图仍然存在异常、初次治疗效果较差的癫痫患者容易发展为难治性癫痫患者。
Objective To study and analyze the early predictors of refractory epilepsy and provide a theoretical basis for clinical treatment. Methods 200 outpatients were selected from November 2009 to November 2011. The patients were divided into two groups according to their illness: experimental group (120 cases) and control group (80 cases). Observe patient general information, type of attack, family history, history of illness, brain injury, mental state and therapeutic effect. Study of epilepsy prone to develop refractory epilepsy predictors. Results The experimental group had mental retardation at early stage (P <0.01). After the treatment, EEG abnormality still existed in the experimental group (P <0.01). The onset of attack before the first hospitalization was more than 10 times (P <0.01). Conclusion There are many epileptic seizures before treatment, accompanied by mental retardation. After the treatment, the EEG is still abnormal. Patients with poor initial treatment may develop epilepsy patients with refractory epilepsy.