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目的 初步测定正常中国儿童的胃肠传输时间并探讨胃肠传输时间对小儿便秘的病因、诊断和分型的意义。方法 研究对象分为对照组和便秘组。对照组 3 3例 ,男 2 1例 ,女 12例 ,平均年龄 5岁。便秘组 2 5例 ,男 15例 ,女 10例 ,平均年龄 7岁 ,均符合Benninga的便秘诊断标准。应用简化的不透X线标记物追踪法 ,即多次口服标记物一次摄片法测定正常和便秘儿童的全胃肠传输时间 (Totalgastrointestinaltransittime,TGITT)和节段性结肠传输时间 ,包括 :右半结肠传输时间 (Rightcolonictransittime ,RCTT) ;左半结肠传输时间 (Leftcolonictransittime ,LCTT)和直肠乙状结肠传输时间(Rectosigmoidcolonictransittime ,RSTT) ;部分患儿联合应用X线排便造影 ,探讨便秘的诊断和分型 ;结果 正常儿童的TGITT ,RCTT ,LCTT和RSTT分别为 2 8 7± 7 7小时、7 5± 3 2小时、6 5± 3 8小时和 13 4± 5 6小时 ;便秘组的TGITT ,LCTT和RSTT较对照组明显延长 (92 2± 5 5 5小时vs 2 8 7± 7 7小时 ,P <0 0 0 1;16 9± 12 6小时vs 6 5± 3 8小时 ,P <0 0 1;和 61 5± 2 9 0小时vs 13 4± 5 6小时 ,P <0 0 0 1)。RCTT无显著变化。X线排便造影显示直肠前突、会阴下降综合征和耻骨直肠肌痉挛综合征各 1例。结论 首次?
Objective To determine the gastrointestinal transit time of normal Chinese children and to explore the significance of gastrointestinal transit time on the etiology, diagnosis and classification of pediatric constipation. Methods The subjects were divided into control group and constipation group. The control group of 33 patients, 21 males and 12 females, mean age 5 years. Constipation group 25 cases, 15 males and 10 females, mean age 7 years, are in line with Benninga constipation diagnostic criteria. A simplified radiopaque method using a single oral radiograph with multiple oral markers was used to determine Total Gastrointestinal transit time (TGITT) and segmental colonic transit time in children with normal and constipation including: right half Colonic transit time (RCTT), left colorectal transit time (LCTT) and rectosigmoid transit time (RSTT) were measured. Some children were diagnosed and diagnosed with constipation using X-ray contrast stool. The results were normal The TGITT, RCTT, LCTT and RSTT in children were 287 ± 7 7 hours, 75 ± 3 2 hours, 65 ± 3 8 hours and 134 ± 5 6 hours, respectively. TGITT, LCTT and RSTT in constipation group were higher than those in control group Group was significantly longer (92 2 ± 55 5 hours vs 2 78 ± 7 7 hours, P <0.01 1; 16 9 ± 12 6 hours vs 6 5 ± 38 hours, P 0 01; and 61 5 ± 2900 hours vs 13 4 ± 5 6 hours, P <0 0 0 1). RCTT no significant change. X-ray defecography showed rectocele, perineal descending syndrome and puborectalis muscle spasm syndrome in 1 case. Conclusion for the first time?