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目的：观察恶性胸、腹腔积液，用香菇多糖（ｌｅｎｔｉｎａｎ）腔内注射治疗的疗效。方法：在２７例（男性１５例，女性１２例；年龄５５±ｓ１２ａ）晚期恶性肿瘤病人排放胸、腹水后，用香菇多糖４ｍｇ或８ｍｇ溶于０．９％氯化钠注射液２０ｍＬ中，腔内注射。结果：治疗恶性胸、腹腔积液总有效率为５２％，其中胸腔积液有效率为６７％，腹腔积液有效率为４０％，局部及全身毒副作用小。结论：香菇多糖腔内注射局部治疗恶性胸、腹腔积液疗效满意。
OBJECTIVE: To observe the effect of intralenticular injection of lentinan on malignant pleural and abdominal effusions. METHODS: Twenty-seven patients (15 males, 12 females, age 55±s12 years) with advanced malignant tumors discharged chest and ascites, and then used lentinan 4 mg or 8 mg dissolved in 0.9% sodium chloride injection 20 mL. Internal injection. Results: The total effective rate of malignant pleural effusion and ascitic effusion was 52%. The effective rate of pleural effusion was 67%, and the effective rate of peritoneal effusion was 40%. Local and systemic side effects were small. Conclusion: The intracavernous injection of lentinan was effective in the treatment of malignant thoracic and abdominal effusions.