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观察正常儿童与变应性鼻炎患儿外周血T细胞亚群分布的差异。方法:用间接免疫荧光法随机检测儿童变应性鼻炎组16例和正常对照组20例,并进行统计学分析。结果:变应性鼻炎组外周血中CD3、CD4、CD8较对照组均有明显下降。结论:T细胞亚群分布的改变是变态反应性疾病免疫功能紊乱的重要环节,可以作为变应性疾病的监测指标。
To observe the distribution of T cell subsets in peripheral blood of normal children and children with allergic rhinitis. Methods: Indirect immunofluorescence method was used to detect 16 children with allergic rhinitis randomly and 20 normal controls. Statistical analysis was performed. Results: The levels of CD3, CD4 and CD8 in peripheral blood of allergic rhinitis group were significantly lower than those in control group. Conclusion: The change of distribution of T cell subsets is an important part of immune dysfunction in allergic diseases and can be used as a monitoring indicator of allergic diseases.