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目的:探讨盆底型子宫内膜异位症(EMs)患者行IVF-ET助孕后妊娠结局及妊娠期并发症。方法:回顾性分析行IVF-ET治疗获临床妊娠的盆底型EMs 96个周期(A组),卵巢子宫内膜异位囊肿者107个周期(B组),并选择同期180个周期输卵管因素行IVF-ET助孕获临床妊娠者为对照组(C组)。分析比较各组患者行IVF-ET助孕的妊娠结局及妊娠期并发症。结果:A组早产率显著低于B组(9.38%vs 21.50%,P<0.05);流产率(25.00%vs 12.78%)及单胎流产率(35.00%vs 17.31%)明显高于C组,差异有统计学意义(P<0.05);异位妊娠发生率略高于B组(2.08%vs 1.87%),低于C组(6.67%),但3组间无统计学差异(P=0.072)。A组和B组妊娠期并发症发生率明显高于C组(30.21%vs 31.78%vs 16.11%,P<0.05),但A、B组间无统计学差异(P>0.05)。其中A组和B组子痫前期(8.33%vs 9.35%)、前置胎盘(9.38%vs 10.28%)发生率显著高于C组(2.78%;3.33%);A组先兆流产率高于B组和C组(18.75%vs 14.02%vs 8.33%),且与C组差异有统计学意义(P<0.05)。结论:盆底型EMs患者行IVF-ET助孕其自然流产率显著高于输卵管不孕患者,早产率较卵巢型EMs降低;妊娠期并发症较输卵管不孕患者明显增多,主要表现在子痫前期、前置胎盘及先兆流产3个方面,而与卵巢型EMs无统计学差异。
Objective: To investigate the pregnancy outcome and pregnancy complications after IVF-ET assisted pregnancy in patients with pelvic floor endometriosis (EMs). Methods: Ninety-six cycles of pelvic floor type EMs (group A) and 107 cycles of ovarian endometriosis (group B) with IVF-ET were retrospectively analyzed. One hundred and eighty cycles of oviduct Line IVF-ET pregnancy-assisted pregnancy were control group (C group). Analysis and comparison of IVF-ET pregnancy outcomes and pregnancy complications in each group of patients. Results: The preterm birth rate in group A was significantly lower than that in group B (9.38% vs 21.50%, P <0.05). The miscarriage rate (25.00% vs 12.78%) and single abortion rate (35.00% vs 17.31% The difference was statistically significant (P <0.05). The incidence of ectopic pregnancy was slightly higher than that of group B (2.08% vs 1.87%), lower than that of group C (6.67%), but there was no significant difference between the three groups (P = 0.072 ). The incidence of pregnancy complications in group A and group B was significantly higher than that in group C (30.21% vs 31.78% vs 16.11%, P <0.05). However, there was no significant difference between groups A and B (P> 0.05). The incidences of preeclampsia (8.33% vs 9.35%) and placenta previa (9.38% vs 10.28%) in group A and group B were significantly higher than those in group C (2.78%; 3.33% Group and group C (18.75% vs 14.02% vs 8.33%, respectively), and there was a significant difference between group C and C (P <0.05). Conclusions: The spontaneous abortion rate of IVF-ET-assisted pregnancy in patients with pelvic floor EMs is significantly higher than that of tubal infertility, and the preterm birth rate is lower than that of ovarian EMs. Complications during pregnancy are significantly higher than tubal infertility patients, mainly in eclampsia Pre-placenta previa and threatened abortion three aspects, and ovarian EMs no significant difference.