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目的:评价头孢替唑单剂量给药对剖宫产产妇术后预防切口感染的效果。方法:选取2015年2月—2017年2月间收治的剖宫产手术患者92例临床资料,将其分为常规组和观察组,每组46例;常规组产妇给予第3代头孢菌素(头孢噻肟)和甲硝唑术后预防切口感染;观察组产妇给予第1代头孢菌素(头孢噻吩)单剂量预防切口感染;评价两组产妇用药后抗菌药物使用时间、抗菌药物用药费用和患者对用药后的满意度,以及剖宫产手术切口感染的发生率的变化情况。结果:观察组患者对用药治疗的满意度高于常规组(P<0.05),剖宫产手术切口感染的发生率与常规组比较其差异无统计学意义(P>0.05),抗菌药物使用时间、抗菌药物用药费用均优于常规组(P<0.05)。结论:头孢噻肟单剂量对预防剖宫产产妇手术切口感染的效果较为确切,可有效预防切口感染的发生,减少了抗菌药物费用,提高了产妇对治疗的满意度。
Objective: To evaluate the effect of ceftezole single dose on postoperative wound infection prevention in cesarean section. Methods: Ninety-two cases of cesarean section were selected from February 2015 to February 2017. The clinical data were divided into routine group and observation group with 46 cases in each group. The third-generation cephalosporins (Cefotaxime) and metronidazole to prevent incision infection; the first group of mothers in the observation group were given cefotaxime (cefalotin) to prevent incision infection; the two groups of maternal drug use time after antibiotics, antimicrobial drug costs And patient satisfaction after medication, as well as changes in the incidence of cesarean section incision infection. Results: The patients in the observation group were more satisfied with the drug treatment than those in the conventional group (P <0.05). The incidence of incision infection in cesarean section was not significantly different from that in the conventional group (P> 0.05) , Antimicrobial drug costs were superior to the conventional group (P <0.05). Conclusion: The single dose of cefotaxime is effective in preventing incisional infection of cesarean section, which can effectively prevent incision infection, reduce the cost of antimicrobial drugs, and improve the satisfaction of maternal treatment.