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胃肠道间质瘤﹙gastrointestinal stromal tumors,GIST﹚是最常见的消化道非上皮细胞性肿瘤,由Mazur和Clark[1]于1983年首先提出,是一类非定向分化的间叶肿瘤,起源于胃肠道固有肌层和粘膜肌层,由梭形细胞和上皮样细胞组成,约占该部位原发性肿瘤的1.2%。研究证明,以往诊断的胃肠道平滑肌瘤及神经鞘瘤大多属于间质瘤,间质瘤比平滑肌瘤多见。胃是消化道间质瘤的最好发部位。
Gastrointestinal stromal tumors (GISTs), the most common gastrointestinal non-epithelial tumors, were first proposed by Mazur and Clark [1] in 1983 and are a group of non-directional differentiated mesenchymal tumors of origin In the gastrointestinal tract of the muscularis propria and muscularis mucosa, composed of spindle cells and epithelial cells, accounting for about 1.2% of the primary tumor in the area. Studies have shown that in the past the diagnosis of gastrointestinal leiomyoma and schwannomas mostly belong to stromal tumors, stromal tumors more common than leiomyoma. Stomach is the best site for gastrointestinal stromal tumors.