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目的探讨急性有机磷农药中毒后迟发性神经病的临床特点,以提高早期诊断及治疗效果。方法回顾30例迟发性多发性神经病发生的时间、症状及体症,结合辅助检查,进行系统分析。结果 30例迟发性多发性神经病患者均为口服中毒,潜伏期为10～32d,平均18d。主要表现为肢体末端开始的感觉和运动障碍,表现为疼痛、麻木、无力、肌肉萎缩、腱反射减弱或消失,肌电图示神经源性损害。用糖皮质激素、B族维生素等综合治疗,大部分预后良好。结论迟发性多发性神经病经早期诊断,积极治疗,预后一般良好,激素治疗可加速神经功能恢复。
Objective To investigate the clinical features of delayed neuropathy after acute organophosphorus pesticide poisoning in order to improve the early diagnosis and treatment effect. Methods Thirty patients with delayed polyneuropathy were retrospectively analyzed for the time, symptoms and physical signs, combined with the auxiliary examination. Results 30 patients with delayed polyneuropathy were oral poisoning, the incubation period was 10 ~ 32d, an average of 18d. Mainly for the beginning of the extremities of the sensory and motor disorders, manifested as pain, numbness, weakness, muscle atrophy, tendon reflexes diminished or disappeared, EMG-induced neurogenic damage. With glucocorticoid, B vitamins and other comprehensive treatment, most of the prognosis is good. Conclusion Delayed polyneuropathy by early diagnosis, active treatment, the prognosis is generally good, hormone therapy can accelerate the recovery of nerve function.