5-Fu作为一种抗代谢药治疗恶性肿瘤已应用多年,近几年眼科用于抗青光眼滤过术后,促进滤过形成及人工晶体植入术后渗出膜的吸收,取得了较好疗效。现报告一例5-Fu致角膜上皮缺损的毒副反应。 患者 男,60岁。渐进性视力下降3年,于1989年11月15日入院。眼部检查:视力:右眼手动,左眼指数。晶体混浊均匀,以右眼为甚。视功能佳。诊断:双眼老年性白内障成熟期。11月20日局麻下 5-Fu has been used as an antimetabolite in the treatment of malignant tumors for many years. In recent years, ophthalmology has been used for anti-glaucoma filtration, which promotes the formation of filtration and the absorption of oozing membrane after intraocular lens implantation and has achieved good results Efficacy. Now report a case of 5-Fu corneal epithelial defects caused by toxicity. Male patient, 60 years old. Progressive vision loss for 3 years, on November 15, 1989 admission. Eye examination: visual acuity: right eye manual, left eye index. Crystal uniform opacity, to the right eye is even. Good visual function. Diagnosis: Both eyes cataract maturation. November 20 under local anesthesia