2. 您的位置
3. 首页
4. 期刊论文
5. RNA-binding proteins in neurological diseases

RNA-binding proteins in neurological diseases

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：guoyh

【摘 要】

：

Emerging studies support that RNA-binding proteins(RBPs)play critical roles in human biology and pathogenesis.RBPs are essential players in RNA processing and m

【作 者】

：

ZHOU HuaLin MANGELSDORF Marie 

【机 构】

：

InstituteofBiophysics,QueenslandBrainInstitute,DepartmentofNeurology

【出 处】

：

中国科学：生命科学英文版

【发表日期】

：

2014年4期

【关键词】

：

RNA结合蛋白 神经系统疾病 RNA加工 稳定性控制 MRNA 人类生物学 RNA剪接 发病机制 RNA-binding proteins  post-tran 

【基金项目】

：

Zhou HuaLin is supported by National Basic Research Program of China(2013CB917803),research fund for the State Key Laboratory of Cog-nitive Neuroscience and Learning from Institute of Biophysics,Chine

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Emerging studies support that RNA-binding proteins(RBPs)play critical roles in human biology and pathogenesis.RBPs are essential players in RNA processing and metabolism,including pre-mRNA splicing,polyadenylation,transport,surveillance,mRNA localization,

其他文献

Newly discovered insect RNA viruses in China

Insects are a group of arthropods and the largest group of animals on Earth,with over one million species described to date.Like other life forms,insects suffer

期刊

RNA病毒昆虫病毒中国节肢动物生物控制剂细胞生物学生命形式经济损失insect virus Wuhan Nodavirus Dendroli

Atomic force microscopy imaging of live mammalian cells

Atomic force microscopy (AFM) was used to examine the morphology of live mammalian adherent and suspended cells. Time-lapse AFM was used to record the locomotio

期刊

原子力显微镜AFM成像哺乳动物活细胞聚二甲基硅氧烷细胞形态神经细胞重组细胞atomic force microscopy cell locom

Establishment of a transgenic mouse model with liver-specific expression of secretory immunoglobuli

Mutation of mevalonate kinase(MVK) is thought to account for most cases of hyperimmunoglobulinemia D syndrome(HIDS) with recurrent fever.However,its mechanism a

期刊

转基因小鼠模型血清免疫球蛋白分泌型特异性表达肝脏SOUTHERN杂交反转录PCRHIDSsIgD liver-specific express

A consensus linkage map of common carp （Cyprinus carpio L.） to compare the distribution and variatio

The ability to detect and identify quantitative trait loci (QTLs) in a single population is often limited. Analyzing multiple populations in QTL analysis improv

期刊

QTLS生长性状遗传连锁图谱鲤鱼等位基因变异QTL检测协商数量性状座位common carp consensus map comparati

Identification of a suitable endogenous control gene in porcine blastocysts for use in quantitative

To obtain reliable results in quantitative PCR (qPCR) reactions, an endogenous control (EC) gene is needed to correct for systematic variations. In this study,

期刊

microRNAPCR分析控制基因囊胚miRNA猪TAQMAN体细胞核移植endogenous control gene quantitati

A Helm model for microRNA regulation in cell fate decision and conversion

microRNAs(miRNAs)constitute a unique class of endogenous small non-coding RNAs that regulate gene expression post-transcriptionally.Studies over the past decade

期刊

调控基因表达细胞行为MICRORNAmiRNA小分子RNA胚胎干细胞模型运转miRNA（s） cell fate development

NK cells play a significant role in immunosurveillance at the early stage of MLL-AF9 acute myeloid l

Acute myeloid leukemia(AML) is an aggressive hematological malignancy, and the mechanism underlying immune system involvement in leukemia development is unclear

期刊

白血病细胞NK细胞早期阶段CD226免疫系统相互作用急性恶性血液病acute myeloid leukemianatural killer c

Progress in defining heterogeneity and modeling periglomerular cells in the olfactory bulb

In recent years the evolution of olfactory bulb periglomerular cells,as well as the function of periglomerular cells in olfactory encoding,has attracted increas

期刊

细胞类型异质性建模嗅球神经信息编码定义嗅觉系统分类标准periglomerular cell patch-clamp modeling an

Physical characteristics of Chinese Hakka

Using standard and internationally validated methods,86 anthropologic characteristics were determined in 650 male(305 from urban areas and 345 from rural areas)

期刊

物理特性客家人中国人类学特征农村地区统计学分析主成分分析使用标准somatoscopy ethnicity Hakka China

Not just a sponge： new functions of circular RNAs discovered

<正>One of the most exciting findings in RNA biology is the discovery of numerous circular RNAs(circ RNA)in mammalian genome.Once being considered as low abunda

期刊

RNA圆形内含子序列海绵剪接位点动物基因组生物合成副产品