负压封闭引流技术来源于外科引流的观念。医生们在长期临床实践中总结出:通过特定的方法(如各类导管及引流材料)对感染部位进行引流,保持创面清洁,可促进创面愈合。自1992年德国Fleischmann博士首创封闭负压引流技术以来,各种皮肤及软组织缺损及感染创面的治疗进入了一个崭新的时代[1]。本文就负压创面疗法(Negative pressure wound therapy NPWT)的作用机制的研究及应用与改良的进展予以 Negative pressure drainage technology from the concept of surgical drainage. In the long-term clinical practice, doctors concluded that wound healing can be promoted by using specific methods (such as various types of catheters and drainage materials) to drain the infected site and keep the wound clean. Since 1992, the first German doctor Fleischmann closed vacuum drainage technology, a variety of skin and soft tissue defects and wounds treatment has entered a new era [1]. In this paper, the mechanism of negative pressure wound therapy (Negative pressure wound therapy NPWT) research and application of the mechanism of improvement to be