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1985年1月～1989年3月对164例食管癌进行放射治疗,其中分不均等放疗Ⅰ组46例,每日剂量分割为500cGy,胸前垂直野(A)→125cGy侧野(B)→125cGy,侧野(C)→125cGy,侧野B→125cGy,侧野C;对照组46例,为常规均等放疗,每日1次,200cGy,A、B、C轮照,每周5次。不均等Ⅱ组,剂量分割为600cGy(A)→100cGy(B)→100cGy(C)→100cGy(A)→100cGy(B);同期对照组36例为常规放疗。各组肿瘤总量均为7000cGy。结果:1年、3年生存率不均等Ⅰ组为60％和30％,对照组为39％和13％,两组均P<0.05;不均等放疗Ⅱ组为61％和35％,对照组为36％和14％,两组均P<0.05。因此,不均等组近期疗效优于对照均等组。5年生存率不均等Ⅰ组略高于对照组,分别为13％(6/46)和10.8％(5/46),差异无显著性。
Radiotherapy was performed on 164 cases of esophageal cancer from January 1985 to March 1989, including 46 cases of inhomogeneous radiotherapy in group I. The daily dose was divided into 500 cGy, and chest vertical field (A)→125 cGy lateral field (B)→ 125cGy, lateral (C)→125cGy, lateral field B→125cGy, lateral field C; 46 patients in the control group, conventional equal radiotherapy, once daily, 200cGy, A, B, C photo, 5 times per week. In the unequal group II, the dose was divided into 600cGy(A)→100cGy(B)→100cGy(C)→100cGy(A)→100cGy(B); in the control group, 36 cases were conventional radiotherapy. The total tumor volume in each group was 7000 cGy. Results: The 1-year and 3-year survival inequalities were 60% and 30% in group I and 39% and 13% in control group, respectively; P<0.05 in both groups; 61% and 35% in unequal radiotherapy group II, control group At 36% and 14%, both groups were P<0.05. Therefore, the short-term efficacy of the unequal group was better than that of the control equivalent group. The 5-year survival rate in the unequal I group was slightly higher than that in the control group, which was 13% (6/46) and 10.8% (5/46) respectively. The difference was not significant.