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目的:分析慢性肾脏病(CKD)患者矿物质和骨代谢紊乱(CKD-MBD)的早期诊疗体会。方法:选取80例CKD-MBD伴低骨密度(BMD)患者作为观察对象,随机将其分为对照组与观察组各40例,对照组给予常规治疗,观察组常规治疗的基础上在皮下注射降钙素,治疗前后对比两组的股骨颈骨、腰椎BMD。结果:(1)治疗后,观察组的腰椎、股骨颈BMD均明显低于对照组(P<0.05)。结论:MDB是CKD的常见并发症,在确诊后应及时给予碳酸钙、骨化三醇与降钙素联合治疗,疗效确切。
Objective: To analyze the early diagnosis and treatment of CKD-MBD in patients with chronic kidney disease (CKD). Methods: Eighty patients with CKD-MBD accompanied with low BMD were randomly divided into the control group and the observation group, 40 cases in each group. The control group was given routine treatment. On the basis of conventional treatment, Calcitonin, before and after treatment of two groups of femoral neck bone, lumbar spine BMD. Results: (1) After treatment, the lumbar spine and femoral neck BMD in the observation group were significantly lower than those in the control group (P <0.05). Conclusion: MDB is a common complication of CKD. Calcium carbonate, calcitriol and calcitonin should be given timely after diagnosis. The curative effect is correct.