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目的探讨百令片对透析患者血钙、血磷及甲状旁腺激素水平的影响。方法选取2016年2月—9月于温州市中心医院透析中心收治的Ⅳ~Ⅴ期慢性肾病患者30例,试验前,患者在透析期间均给予常规治疗;试验后,患者在常规治疗基础上添加百令片治疗,观察12周。比较患者试验前后血磷、血钙、甲状旁腺素及清蛋白、体质指数(BMI)。结果试验后,27例(90.0%)患者血钙、血磷水平恢复正常,患者血磷、甲状旁腺激素水平低于试验前,血钙浓度高于试验前(P<0.05)。患者试验前后血清蛋白水平、BMI比较,差异无统计学意义(P>0.05)。结论百令片可有效调节透析患者钙磷代谢平衡,降低甲状旁腺激素水平,但仍需大样本的研究证实。
Objective To investigate the effect of Bailing tablets on serum calcium, phosphorus and parathyroid hormone in dialysis patients. Methods Thirty patients with stage Ⅳ ~ Ⅴ chronic renal disease were enrolled in the dialysis center of Wenzhou Central Hospital from February to September in 2016. Before the experiment, patients were given routine treatment during dialysis. After the trial, the patients were added on the basis of routine treatment Liling tablets treatment, observed for 12 weeks. Blood phosphorus, serum calcium, parathyroid hormone and albumin, body mass index (BMI) were compared before and after the trial. Results After the test, blood calcium and phosphorus levels returned to normal in 27 patients (90.0%). The levels of serum phosphorus and parathyroid hormone in patients were lower than those before the test, and the levels of serum calcium were higher than those before the test (P <0.05). There was no significant difference in serum protein level and BMI before and after the trial (P> 0.05). Conclusion Bailing tablets can effectively regulate dialysis patients calcium and phosphorus metabolism balance, reduce the level of parathyroid hormone, but still need a large sample of studies confirmed.