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目的探究初诊2型糖尿病经诺和锐治疗(短期强化)效果及对机体胰岛β细胞功能的影响。方法针对80例初诊2型糖尿病患者实施诺和锐治疗(短期强化),治疗后观察患者的糖化血红蛋白(Hb A1c)、空腹(FPG)及餐后2 h血糖(2 h PG)等指标,评价诺和锐治疗(短期强化)的效果。入选的80例患者均为该院2015年3月—2017年1月间收治。结果经过诺和锐治疗(短期强化)后,患者的糖化血红蛋白(Hb A1c)、空腹(FPG)及餐后2 h血糖(2 h PG)等指标均出现明显改善,且和治疗前比较差异有统计学意义;同时患者的胰岛素分泌指数和敏感指数均出现改善,差异有统计学意义(P<0.05)。结论初诊2型糖尿病经诺和锐治疗(短期强化)效果良好,能够改善患者的血糖水平,同时该方法利于患者胰岛β细胞的敏感性提升,因此值得在临床中借鉴使用。
Objective To explore the effect of Novo-Rui treatment (short-term enhancement) and the function of pancreatic β-cell in newly diagnosed type 2 diabetic patients. Methods A total of 80 patients with newly diagnosed type 2 diabetes were enrolled in Nuo-Rui-Rui treatment group. Hb A1c, fasting plasma glucose (FPG) and 2-hour postprandial blood glucose (2 h PG) Connaught and sharp treatment (short-term strengthening) effect. The selected 80 patients were treated in the hospital from March 2015 to January 2017. Results Noore and sharp treatment (short-term intensive), patients with Hb A1c, fasting (FPG) and 2 h postprandial blood glucose (2 h PG) and other indicators were significantly improved, and compared with before treatment were Statistical significance; At the same time, patients with insulin secretion index and sensitivity index showed an improvement, the difference was statistically significant (P <0.05). Conclusions The newly diagnosed type 2 diabetes mellitus (NO) treated with Novo-Rui (short-term intensive) has a good effect and can improve the blood glucose level of patients. Meanwhile, this method is beneficial to the increase of pancreatic β-cell sensitivity in patients with type 2 diabetes mellitus, so it is worth to be used in clinic.