本文选用顺铂、长春新碱、平阳霉素全身化疗.治疗晚期食管癌31例,缓解率为64.5％,有效率77.4％。在此基础上,同时佐用顺铂液(0.08％)食管局部灌注,作为综合治疗组,治疗晚期食管癌34例,缓解率为79.3％,有效率为88.1％。两组对比,综合治疗组疗效提高,副作用相似,最常见的副作用是胃肠道反应,未见有明显骨髓抑制及心、肝、肾功能损害。 This article selected cisplatin, vincristine, Pingyangmycin chemotherapy. Treatment of advanced esophageal cancer in 31 cases, the remission rate was 64.5%, an effective rate of 77.4%. On this basis, concurrent use of cisplatin solution (0.08%) local esophageal perfusion as a comprehensive treatment group, treatment of advanced esophageal cancer in 34 cases, the response rate was 79.3%, the effective rate was 88.1%. In comparison between the two groups, the efficacy of the comprehensive treatment group was improved and the side effects were similar. The most common side effect was gastrointestinal reaction. There was no obvious bone marrow suppression and heart, liver and kidney function impairment.