论文部分内容阅读
目的:旨对儿科急性上呼吸道感染住院患儿临床抗生素应用情况进行系统分析,以为临床合理用药提供更多参考依据。方法:对2013年1月~2014年5月间笔者单位收治的300例急性上呼吸道感染住院患儿抗生素使用情况进行系统的回顾性分析。结果:300例儿科急性上呼吸道感染住院患儿临床应用抗生素治疗294例(98.0%)。使用单一品种抗生素101例(34.3%),联合应用或者与其他药物联合应用治疗193例(65.6%)。294例应用抗生素治疗患儿中,青霉素类抗生素临床应用率居首(66.7%),其他依次为头孢菌素类(38.1%)、大环内脂类(24.1%),其他抗生素类药(6.8%)。经临床抗生素治疗之后,治愈226例(76.9%),好转65例(22.1%),无效3例(1.0%),但经对症治疗后痊愈;本组无死亡病例。结论:儿科急性上呼吸道感染住院患儿在临床应用抗生素方面存在一定的不合理性;因此,全面提高临床医师业务水平,严格执行相关疾病的抗生素使用指南,是确保抗生素合理的最要手段。
Objective: To systematically analyze the clinical application of antibiotics in hospitalized children with acute upper respiratory tract infection in pediatrics, in order to provide more reference for clinical rational drug use. Methods: A retrospective analysis was performed on the antibiotic use in 300 hospitalized children with acute upper respiratory tract infection admitted to our hospital from January 2013 to May 2014. Results: A total of 294 cases (98.0%) were treated with antibiotics in 300 pediatric patients with acute upper respiratory tract infection. A single variety of antibiotics in 101 cases (34.3%), combined or in combination with other drugs in 193 cases (65.6%). Among the 294 patients treated with antibiotics, the clinical application of penicillin antibiotics was the highest (66.7%), followed by cephalosporins (38.1%), macrolides (24.1%) and other antibiotics %). After clinical antibiotic treatment, 226 cases (76.9%) were cured, 65 cases (22.1%) were improved, 3 cases (1.0%) were invalid, but recovered after symptomatic treatment. There were no deaths in this group. CONCLUSIONS: Inpatients with pediatric acute upper respiratory tract infection have some irrationality in clinical application of antibiotics. Therefore, it is the most necessary means to ensure the rational use of antibiotics to improve clinicians’ professional skills and strictly enforce the guidelines on the use of antibiotics.