论文部分内容阅读
目的探讨舒腰灵冲剂主治腰椎间盘突出症的治疗效果及其作用机制。方法与结果通过动物实验证明，舒腰灵冲剂小鼠一次灌胃最大耐受量为12g／kg，并且具有明显抗角叉菜胶致大鼠实验性足跖炎性肿胀，降低乙酸引起小鼠腹腔毛细血管通透性增高，减轻乙酸引起小鼠致痛作用，以及减低全血粘度和红细胞压积作用。另外通过61例腰椎间盘突出症采用日服舒腰灵冲剂治疗，优良率达90．3％。结论舒腰灵冲剂具有明显抗炎止痛和改善血液流变学作用，对临床腰椎间盘突出症有较好疗效。
Objective To investigate the therapeutic effect and mechanism of Shuluoling Granules in treating lumbar disc herniation. METHODS AND RESULTS: Animal experiments showed that the maximum tolerated dose per dose of Shou Yao Ling granules was 12 g/kg, and there was a significant anti-carrageenan-induced inflammatory swelling of the paw in rats, which reduced acetic acid-induced mice. Increased permeability of the peritoneal capillaries, reduced acetic acid-induced pain in mice, and decreased whole blood viscosity and hematocrit. In addition, 61 cases of lumbar disc herniation were treated with Shufuling Granule on daily basis, and the excellent and good rate was 90.3%. Conclusion Shuluoling Granule has obvious anti-inflammatory and analgesic effects and can improve hemorheology. It has good curative effect on clinical lumbar disc herniation.