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现已广泛应用细胞融合技术制造鼠型单克隆抗体来研究人白细胞分化抗原。这些单克隆抗体,以往是以Leu3a、T_4、NU-T_H/1等各自不同的名称来命名的。近2～3年来趋向于根据CD(Cluster of differentiation)分类的表示方法而称之为CD_2,CD_2,CD_3,CD_4抗体……。CD分类是人白细胞分化抗原及识别分化抗原的单克隆抗体的世界统一的分类方法,不管是基础或是临床研究人员对CD分类都应很好的理解和正确地使用。 1、CD分类的背景自发明单克隆抗体技术以来,许多部门对已知抗原或未知抗原制出单克隆抗体,如对白细胞膜上的未知分化抗原制出单克隆抗体,这就意味着发现了新的抗原,对以后的研究和发
It has been widely used to make murine monoclonal antibody to study human leukocyte differentiation antigen. These monoclonal antibodies, in the past have been Leu3a, T_4, NU-T_H / 1, respectively, the names of different names. In the recent 2 ~ 3 years, it tends to be called CD_2, CD_2, CD_3 and CD_4 antibody according to the classification of CD (Cluster of differentiation). The CD classification is a world-class classification of human leukocyte differentiation antigens and monoclonal antibodies that recognize differentiated antigens. The classification of CDs should be well understood and correctly used by clinicians regardless of their classification. Background to the CD Classification Since the invention of monoclonal antibodies, many departments have developed monoclonal antibodies against known or unknown antigens, such as monoclonal antibodies against unknown differentiated antigens on leukocyte membranes, which means that new Of the antigen, for future research and hair