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阿糖腺苷(Ara-A)是一种颇有希望的抗单疱性角膜—色素膜炎药物。但溶解度极低,临床应用受到很大限制,局部应用常配成3%眼膏。混悬液结膜下注射治疗实验性单疱虹膜炎有效,但有刺激,且易形成肉芽肿。肌肉注射治疗实验性单疱虹膜炎无效,可能与形成肉芽肿妨碍吸收有关。静脉注射 Ara-A 治疗人眼单疱角膜—色素膜炎有效。由于药物溶解度小,为获得必须的用药剂量,静脉注射须给予大量的液体负荷,为其缺点。次黄嘌呤阿糖苷(Ara hypoxanthine Ara
Ara-A is a promising anti-unicellular keratitis pigmentitis drug. However, the solubility is very low, the clinical application is subject to great limitations, topical application often dubbed 3% ointment. Subconjunctival injection of suspension for the treatment of experimental herpes simplex vesicles effective, but stimulating, and easy to form granulomas. Intramuscular injection of experimental herpes simplex iritis invalid, may be related to the formation of granulomas impede the absorption. Intravenous Ara-A treatment of human eye herpes simplex corneal pigmentitis effective. Due to the small solubility of the drug, intravenous injection requires a large amount of fluid load in order to obtain the necessary dosage, which is a disadvantage. Hypoxanthine Ara