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尽管对急性肾功能衰竭(ARF)的治疗取得了重大的进展,但死亡率仍然很高。作者将235例ARF患者分为两组进行分析。一组为ARF伴有黄疸67例;一组为ARF无黄疸168例。研究发现两组死亡率有明显差异(P<0.05)。ARF有黄疸组为57％(38/67例);无黄疸组为42％(71/168例)。有黄疸的ARF患者的病因,最常见的是胆管炎和中毒或败血性流产,胆道手术后患者大部分都有革兰氏阴性菌败血症的证据。流产后ARF有黄疸者死亡率为42％;而产后患者为25％。将预后较好的产后和流产者除外。其余黄疸者的死亡率为74％。
Although significant progress has been made in the treatment of acute renal failure (ARF), the mortality rate remains high. The authors divided 235 ARF patients into two groups for analysis. A group of 67 cases with ARF accompanied by jaundice; a group of 168 cases without jaundice ARF. The study found significant differences in mortality between the two groups (P <0.05). ARF jaundice group was 57% (38/67 cases); no jaundice group was 42% (71/168 cases). The etiology of ARF patients with jaundice, the most common is cholangitis and poisoning or septic abortion, with evidence of Gram-negative sepsis in most patients after biliary surgery. ARF jaundice after abortion mortality was 42%; postpartum patients were 25%. The prognosis is better except for postpartum and abortion. The remaining jaundice mortality rate was 74%.