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目的:探讨胸腺上皮肿瘤多层螺旋CT(MSCT)影像特征与其WHO组织病理学分型间的相关性。方法:回顾性分析44例经手术病理证实的胸腺上皮肿瘤患者的术前MSCT表现,并将其按WHO组织病理学分型的简化型分组进行对比。结果:胸腺上皮肿瘤的MSCT侵袭性征象包括轮廓不规则、肿瘤-心脏-大血管接触面(MCI)呈灌注型、纵隔脂肪线消失及瘤-肺界面毛刺影,这些特征在高危胸腺瘤及胸腺癌中均较低危胸腺瘤中更常见(P均<0.05),而肿瘤周围淋巴结肿大在胸腺癌中出现频率较低危胸腺瘤及高危胸腺瘤高(P均<0.05)。结论:MSCT能够反映胸腺上皮肿瘤的生物学特性,具有预测其组织学类型的潜力。
Objective: To investigate the correlation between MSCT features of thymus epithelial tumor and its histopathological classification. Methods: The preoperative MSCT findings of 44 patients with thymic epithelial tumors confirmed by surgery and pathology were retrospectively analyzed. The comparisons were made according to the simplified classification of WHO histopathological classification. Results: The features of MSCT in thymic epithelial tumors include irregular contour, perfusion type of MCI, disappearance of mediastinal fat line and burr shadow of tumor-lung interface. These features are associated with high-risk thymoma and thymus The cancers were more common in lower-risk thymoma (all P <0.05), while the lymphadenopathy around the tumor was more frequent in thymus adenocarcinoma than in low-risk thymoma and high-risk thymoma (all P <0.05). Conclusion: MSCT can reflect the biological characteristics of thymic epithelial tumors and has the potential to predict its histological type.