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目的：观察国产降纤酶治疗急性脑梗死的效果。方法：应用国产降纤酶治疗急性脑梗死４４例，并与低分子右旋糖酐加复方丹参４５例对照。结果：治疗前后神经功能缺损评分，两组治疗均有效，临床疗效判定，降纤酶组总有效率８４．２％，明显优于对照组，特别是基本痊愈和显著进步明显高于对照组；降纤酶能显著降低血浆纤维蛋白原，延长凝血时间，而不影响出血时间、凝血酶原时间。结论：降纤酶治疗急性脑梗死效果明显，毒副作用小。
Objective: To observe the effect of domestic defibrase on acute cerebral infarction. Methods: 44 cases of acute cerebral infarction were treated with domestic defibrase and compared with 45 cases of low molecular dextran and compound Danshen. Results: The score of neurological deficit before and after treatment was effective in both groups. The clinical curative effect was determined. The total effective rate of defibrase was 84.2%, which was significantly better than that of the control group, especially the basic recovery and significant progress were significantly higher than that of the control group. Defibrase can significantly reduce plasma fibrinogen, prolong clotting time, without affecting the bleeding time, prothrombin time. Conclusion: Defibrase is effective in the treatment of acute cerebral infarction with small toxic and side effects.