目的　评价经皮穿刺椎体成形术治疗伴有疼痛或脊柱不稳椎体转移瘤的作用。方法　在CT引导下 5 4位患者 5 7次操作中共 72例次椎体接受经皮穿刺椎体成型术治疗。其中 46次操作为了止痛 ,5次为了稳定脊柱 ,6次二者兼之。采用随访统计对治疗效果评价。结果　在 5 2次止痛操作中 ,39次获得了明显的疼痛症状缓解 ,7次获得轻度缓解 ,6次无改善。随访至 6个月时73.6%的改善效果仍稳定 ,1年 65 .6%的治疗仍有效。针对脊柱稳定性的治疗 ,随访没有发现任何移位、变形等改变。 3次操作由于骨水泥的刺激出现神经放散痛 ,2次操作由于推移肿瘤组织而压迫脊髓。结论　脊柱转移瘤的椎体成型术治疗是一种微创操作 ,其可立刻获得止痛效果并长期有效 ,可维持脊柱稳定防止椎体压缩导致截瘫 Objective To evaluate the role of percutaneous vertebroplasty in the treatment of painful or spondylolistic metastases. Methods A total of 72 cases of vertebral bodies were treated with percutaneous vertebroplasty in 54 patients under CT guidance. Of these 46 operations were for pain relief and 5 for stability of the spine, 6 times for both. Follow-up statistics were used to evaluate the effect of treatment. Results In 52 times of analgesic operation, obvious pain relief was obtained in 39 times, slight relief in 7 times and no improvement in 6 times. At 6 months follow-up, 73.6% of the improvements were still stable and 65.6% of the patients remained active for 1 year. For the treatment of spinal stability, follow-up did not find any shift, deformation and other changes. 3 times due to the stimulation of bone cement neuroendromic pain, 2 times the operation of the tumor tissue as the oppression of the spinal cord. Conclusions Vertebroplasty of spinal metastases is a minimally invasive procedure that provides immediate analgesic efficacy and long-term effectiveness, maintains the stability of the spine and prevents vertebral compression leading to paraplegia