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血浆纤维结合蛋白(FN)是一组高分子糖蛋白,具有多种生物活性,对单核巨噬细胞系统清除血流中的颗粒成份十分重要。临床观察和动物实验结果表明,血管内凝血时FN减少,流行性出血热(EHF)患者的主要病理变化是广泛性血管损伤,且多数病人有凝血象异常,本文目的在于了解EHF患者凝血象异常与血浆FN水平的关系及其临床意义。
Plasma Fibronectin (FN) is a group of macromolecule glycoproteins with a variety of biological activities that are important for the monocyte-macrophage system to remove particulate matter in the bloodstream. Clinical observations and animal experiments show that when the intravascular coagulation FN decreases, the main pathological changes in patients with epidemic hemorrhagic fever (EHF) is extensive vascular injury, and most patients have coagulation abnormalities, the purpose of this paper is to understand the coagulation abnormalities in patients with EHF And plasma FN levels and its clinical significance.