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目的：研究性激素对大鼠前列腺腹叶（ＲＶＰ）内纤维连接蛋白（ＦＮ）表达的影响。方法：Ｗｉｓｔａｒ雄性大鼠５２只随机分为三组：正常对照组，阉割组和阉割后用不同比例雌二醇（Ｅ２）与睾丸酮（Ｔ）处理组（Ｃ＋Ｅ２／Ｔ组），以免疫组化ＡＢＣ法观察ＲＶＰ内ＦＮ的表达。结果：阉割组ＦＮ表达增强（Ｐ＜００５），Ｃ＋Ｅ２／Ｔ组当Ｅ２／Ｔ＞１：２５０时ＦＮ表达明显增强（Ｐ＜００１）。结论：ＲＶＰ内ＦＮ的表达与Ｅ２和Ｔ的含量及平衡状态密切相关。
Objective: To investigate the effect of sex hormones on the expression of fibronectin (FN) in the rat ventral ventricle (RVP). Methods: Fifty-two Wistar male rats were randomly divided into three groups: normal control group, castrated group and estrogen-treated group (C + E2 / T group) ABC method to observe the expression of FN in RVP. Results: The expression of FN was increased in the castration group (P <005). The expression of FN was significantly increased in the E2 + T / T group when E2 / T> 1: 250 (P <001). Conclusion: The expression of FN in RVP is closely related to the contents and balance of E2 and T.