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目的:探究采用紫杉醇联合顺铂化疗方案治疗晚期食道癌的临床疗效和应用价值。方法:选取我院晚期食道癌患者57例,随机分为对照组27例和观察组30例,对照组采用5-氟尿嘧啶联合顺铂治疗,观察组采用紫杉醇联合顺铂治疗,治疗后观察比较两组患者临床疗效和患者不良反应情况。结果:观察组患者治疗总有效率高于对照组(P<0.05),差异有统计学意义;两组患者均未发生任何严重性不良反应。结论:采用紫杉醇联合顺铂治疗晚期食道癌,治疗总有效率高,不良反应少,临床疗效显著,应用价值高。
Objective: To investigate the clinical efficacy and application value of paclitaxel combined with cisplatin chemotherapy in the treatment of advanced esophageal cancer. Methods: Fifty-seven patients with advanced esophageal cancer in our hospital were randomly divided into control group (27 cases) and observation group (30 cases). The control group was treated with 5-fluorouracil and cisplatin. The observation group was treated with paclitaxel and cisplatin. Group clinical efficacy and adverse reactions in patients. Results: The total effective rate of observation group was higher than that of control group (P <0.05), and the difference was statistically significant. No serious adverse reactions occurred in both groups. Conclusion: Paclitaxel combined with cisplatin in the treatment of advanced esophageal cancer, the total effective rate of treatment, fewer adverse reactions, significant clinical effect, high value.