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为了探讨Ｃ—反应蛋白（Ｃ—ｒｅａｃｔｉｖｅＰｒｏｔｅｉｎ，ＣＲＰ）在重症医院感染患者发病进程中的变化及其诊断价值。本文应用激光散射定量分析测定２５例重症医院感染患者和２５例轻症医院感染患者血清ＣＲＰ含量，并与２５例正常人对照分析。结果表明：重症医院感染患者早期的血清ＣＲＰ含量明显高于轻症医院感染患者（Ｐ＜０．０１），而轻症医院感染患者血清ＣＲＰ含量与正常人无明显差异。另外，重症医院感染患者若出现并发症或预后不良时，ＣＲＰ仍维持较高的血浓度。因此，ＣＲＰ定量分析作为一种快速、可靠的检测手段。对早期判断医院感染的严重程度及预后具有重要的价值。
To investigate the changes of C-reactive protein (CRP) in the pathogenesis of severe nosocomial infections and their diagnostic value. In this paper, serum CRP levels in 25 patients with severe nosocomial infections and 25 patients with mild nosocomial infections were determined by laser light scattering quantitative analysis and compared with 25 normal controls. The results showed that the serum CRP levels in patients with severe nosocomial infections were significantly higher than those in patients with mild nosocomial infections (P <0.01), while those in patients with mild nosocomial infections were not significantly different from those in normal subjects. In addition, severe hospital infection in patients with complications or poor prognosis, CRP still maintain a high blood concentration. Therefore, CRP quantitative analysis as a fast, reliable means of detection. Early judgment of the severity of hospital infection and prognosis of great value.