论文部分内容阅读
目的观察静脉滴注尼卡地平治疗高血压急症的降压疗效及安全性。方法入选55例高血压急症并接受静脉滴注尼卡地平治疗2～4h,起始滴速为0.5μg/(kg.min),根据血压调滴速,观察临床症状、不良反应、血压和心率变化。结果总有效率92%,用药后5min血压下降,30min达显效水平,1.5h达最大降压效果并平稳维持至用药结束。不良反应发生率为8.9%,包括面部潮红5%,心悸1.2%,头痛1%,四肢麻木1%,心率增快不明显,在用药30min后复原,用药后无心电图及血生化指标的变化异常。结论静脉滴注尼卡地平能快速、有效、安全地控制高血压急症的血压水平。
Objective To observe the antihypertensive efficacy and safety of intravenous nicardipine in the treatment of hypertensive emergency. Methods Fifty-five patients with acute essential hypertension were treated with nicardipine intravenously for 2 to 4 hours. The initial dripping rate was 0.5 μg / (kg · min). According to the blood pressure drip rate, clinical symptoms, side effects, blood pressure and heart rate Variety. Results The total effective rate of 92%, 5min after administration of blood pressure decreased 30min reached a significant level, 1.5h up to the maximum antihypertensive effect and stable until the end of the medication. The incidence of adverse reactions was 8.9%, including facial flushing 5%, palpitations 1.2%, headache 1%, limbs numbness 1%, heart rate was not significantly increased 30min after drug recovery, no ECG and blood biochemical changes after treatment abnormalities . Conclusion Intravenous nicardipine can rapidly, effectively and safely control the blood pressure of acute essential hypertension.