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［ 目的］ 探讨桥本甲状腺炎的临床病理特点．［ 方法］ 对３４ 例住院手术的桥本甲状腺炎病例进行了临床、病理分析．［ 结果］ 病理观察结果表明，甲状腺滤泡萎缩、消失，大量淋巴细胞浸润，核异型性是诊断桥本甲状腺炎的主要病理变化，其次是淋巴滤泡形成、间质纤维组织增生和滤泡上皮嗜酸性变．［ 结论］ 凡成年女性甲状腺肿大，质较硬，无特殊临床表现时应考虑桥本甲状腺炎，需进一步检查，疑为癌时采用术中快速冷冻病理检查，以明确诊断．
[Objective] To investigate the clinicopathological features of Hashimoto’s thyroiditis. [Methods] The clinical and pathological analysis of 34 Hashimoto’s thyroiditis patients hospitalized were performed. [Results] The pathological results showed that thyroid follicles atrophy and disappearance, a large number of lymphocytic infiltration and nuclear atypia were the main pathological changes in the diagnosis of Hashimoto’s thyroiditis, followed by lymphoid follicle formation, interstitial fibroplasia and follicular epithelium Eosinophilic changes. [Conclusion] Hashimoto’s thyroiditis should be considered in all adult women with goiter, hard quality and no special clinical manifestations. The diagnosis of Hashimoto’s thyroiditis should be further investigated. The intraoperative rapid freezing pathological examination should be used to confirm the diagnosis.